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A total of 62 patients were initially screened across five study centers for eligibility in this study. Of these, 15 patients were excluded due to various reasons: 10 failed the screening, 3 declined participation, 1 was ineligible due to anemia, and 1 was excluded for other reasons. Ultimately, 46 patients met the eligibility criteria and were enrolled to receive the combination treatment of pyrotinib (400 mg orally once daily) and fulvestrant (500 mg intramuscularly, per protocol). These patients were subsequently followed to assess the efficacy and safety of the treatment regimen.
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Ying Wang
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