microscope images (IMAGE)
Caption
On the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains the cytoplasm and proteins red or pink. This method is used in the diagnosis of prostate cancer. Visium technology (in the centre) allows for spatial genetic information to be obtained, enabling the precise study of RNA expression patterns in different areas of the tissue sample. The dots in the image are data points from which gene expression was measured. The main results of the study were obtained using this technology. On the right is a mIHC (multiplex immunohistochemistry) microscope image showing proteins stained with antibodies. This method was used for validation in the study.
Credit
Antti Kiviaho, Tampere University
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