Illustration of the role of exosomes in diabetic cardiomyopathy (DCM). In response to diabetes, normal cardiomyocytes undergo pathological changes, leading to the release of detrimental exosomes. These exosomes carry specific microRNAs (miRNAs), such as m (IMAGE)
Caption
Illustration of the role of exosomes in diabetic cardiomyopathy (DCM). In response to diabetes, normal cardiomyocytes undergo pathological changes, leading to the release of detrimental exosomes. These exosomes carry specific microRNAs (miRNAs), such as miR-1, miR-133a, and miR-126, which have potential as biomarkers for diagnosing DCM, as well as miRNAs like miR-30d, miR-195, miR-21, and miR-208a, which are associated with disease progression and present therapeutic targets.
Credit
Azhar Anwar/Nanjing University, Jizheng Ma/ The Army Engineering University of PLA, Xin Yin/Nanjing University
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License
CC BY