Cross-chiral exponential amplification of an RNA enzyme (IMAGE)
Caption
Salk scientists engineered a right-handed RNA enzyme (bottom left) that can combine left-handed RNA fragments (bottom right) to create a mirror image of itself. The new left-handed RNA enzyme (top right) can then combine right-handed RNA fragments (top left) to produce more of the original right-handed enzyme, restarting the cycle of cross-chiral self-replication. Adapted from Cochrane et al., PNAS 2024.
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Salk Institute
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