Plastic chemical causes causes DNA breakage and chromosome defects in sex cells (IMAGE)
Caption
BBP exposure causes chromosome organization defects in the female germline. Carnoy’s fixed and DAPI-stained images of gonads at the pachytene stage following exposure to DMSO or BBP. Images represent examples of gonads with normal germline configuration (first panel) or various chromosome organization defects in the germline including laggers (second panel), aggregates (third panel), and gaps (fourth panel). Yellow arrowheads indicate the respective defect in each panel. N = 27–31 gonads. Three biological repeats. Scale bar, 5 μm.
Credit
Henderson et al, 2024, PLOS Genetics, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)
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License
CC BY