The induction of autophagy-related genes in astrocytes proves to be a critical mechanism in effectively eliminating Aβ in the brains of AD patients (IMAGE)
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The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is important for cognitive recovery.
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Korea Institute of Science and Technology
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