BAs induce hepatocyte apoptosis by mediating mitochondrial dysfunction through death receptors via independent & dependent pathways (IMAGE)

Xia & He Publishing Inc.

BAs induce hepatocyte apoptosis by mediating mitochondrial dysfunction through death receptors via independent & dependent pathways

Caption

BAs, Bile acid; NTCP, sodium-taurocholate co-transporting polypeptide; FADD, FAS-associated via death domain; BID, BH3 interacting domain death agonist; BAX, Bcl-2-associated X protein; BAK, Bcl-2-antagonist/killer 1; ETC, electron transport chain; mtDNA, mitochondrial DNA; TCA, tricarboxylic acid; mPTP, mitochondrial permeability transition pore; ROS, reactive oxygen species; Cyto C, cytochrome C

Credit

Yanyan Tao, Yuan Peng, Xutao Li, Tianyin Ruan

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

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