Figure 1 (IMAGE)

Institute for Basic Science

Figure 1

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A: Structure of Thermonuclease from Staphylococcus aureus predicted by AlphaFold2. Change in stability upon mutation, ∆∆G (positive values are destabilizing), is plotted as a function of effective strain measured at the mutated site, and in a spherical region near the mutated site, for 491 mutants. The black line shows the median. Statistical correlations are shown for Pearson’s r and Spearman’s ρ.

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Institute for Basic Science

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