OPD maps of living cells and rise in molecular density at mitosis (IMAGE)
Caption
(A) Histone staining images and OI-DIC density imaging of human living cells in the interphase (the phase between cell divisions, left) and mitotic phase (right). The bottom two rows are OI-DIC optical path difference maps, where the optical path length value divided by the thickness of the sample is the refractive index (≅ density) of the sample. (B) The density of the environment surrounding mitotic chromosomes transiently increases during mitosis. The density reaches a maximum in late mitosis (anaphase), when mitotic chromosomes are most condensed.
Credit
Shiori Iida & Kazuhiro Maeshima, National Institute of Genetics, ROIS and Michael Shribak, Marine Biological Laboratory
Usage Restrictions
Only for use with reports of this research.
License
Original content