Image (IMAGE) Higher Education Press Caption Terc-53 functions as a molecular scaffold bringing together Hmmr and Trim25, accelerating Hmmr’s ubiquitination-mediated degradation, which consequently leads to neuroinflammation and cognition decline. Credit Sipeng Wu, Yiqi Cai, Lixiao Zhang, Xiang Li, Xu Liu, Guangkeng Zhou, Hongdi Luo, Renjian Li, Yujia Huo, Zhirong Zhang, Siyi Chen, Jinliang Huang, Jiahao Shi, Shanwei Ding, Zhe Sun, Zizhuo Zhou, Pengcheng Wang, Geng Wang Usage Restrictions none License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.