Fig. 1 (IMAGE)

Osaka University

Fig. 1

Caption

Graphical abstracts. REST_SSO directly modifies REST splicing and RE1 gene expression, whereas both REST_SSO and SRRM4_ASO exhibit antitumor effects in SCLC/NEPCa.

Credit

2024 Shimojo et al., Splice-switching antisense oligonucleotide controlling tumor suppressor REST is a novel therapeutic medicine for neuroendocrine cancer, Molecular Therapy Nucleic Acids

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