The intestinal domination of enterococci promotes the expansion and pathogenicity of S. Tm. (IMAGE)

Research

The intestinal domination of enterococci promotes the expansion and pathogenicity of S. Tm.

Caption

The intestinal domination of enterococci promotes the expansion and pathogenicity of S. Tm. After the oral administration of coumarin glucosides, enterococci inhibit the growth and invasion of S. Tm by hydrolyzing dietary coumarin glycosides to antibacterial aglycones. These catechol aglycones suppress the growth of pathogenic bacteria via causing iron limitation. Meanwhile, coumarin glycosides and their aglycones ameliorate the microbiota dysbiosis of enterococci-mediated polymicrobial infections.

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