Expression of PFDN6 in patients with CRC. (IMAGE)

First Hospital of Jilin University

Expression of PFDN6 in patients with CRC.

Caption

 (A) Principal component (PC) analysis of normal and cancer samples. (B) Differentially expressed genes in normal and cancer samples. (C) Data mining of TCGA Database showed the expression of PFDN6. (D, E) Χ2 test for correlation between PFDN6 expression and different CRC stages (stage I, stage II, stage III and stage IV) and TNM stages. Statistical differences were analysed using Spearman’s test. (F) H&E staining of mice in control (Ctrl), tumour (T), tumour+lymph node metastasis (T+LNM) groups. Scale bar, 100 µm. Magnification times: 200×, 400×. (G) The expression levels of PFDN6 in CRC tumour tissues with or without lymph node metastasis and para-carcinoma tissues were determined by immunohistochemical staining. Magnification times: 200×, 400×. (H) The statistics of (G). The data are expressed as mean±SEM; **p<0.01 vs T+LNM, ***p<0.001 vs Ctrl. CRC, colorectal cancer; FC, fold change; TCGA, The Cancer Genome Atlas; TNM, tumour–node–metastasis.

Credit

By Fenghua Xu, LingYang Kong, Xiao Sun et al.

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License

CC BY-NC

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