(IMAGE)

Kumamoto University

Caption

Due to the 4-hour maturation half-life of the Timer protein's blue-to-red chromophore, we can detect reactivated or recently silenced proviruses with high sensitivity using Timer fluorescence. HIV-Tocky has identified two latent patterns: direct latency, and later latency which initially exhibits transient expression.

Credit

Yorifumi Satou, Kumamoto University

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