Tumor blood vessels produce the angiocrine factor, Sfrp1. (IMAGE)

University of Fukui

Tumor blood vessels produce the angiocrine factor, Sfrp1.

Caption

Aside from providing oxygen and nutrients to the tumor, blood vessels also secrete angiocrine factors. This study revealed that the factor Sfrp1, produced by vascular endothelial cells, plays an essential role in tumor growth by maintaining populations of cancer stem cells and regulating the Wnt signaling pathway.

Credit

Hiroyasu Kidoya from the University of Fukui

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CC BY

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