Patients who use semaglutide for weight loss, like Ozempic, are more likely to continue the medication if they perceive it as effective, even when facing unpleasant side effects, according to Rutgers Health researchers.

Their study, published in Journal of Medical Internet Research, found perceived effectiveness – reductions in weight, appetite or food cravings – was the strongest predictor of satisfaction and intention to continue treatment, regardless of side effects.

UC Irvine scientists used directed evolution to engineer a DNA polymerase that can quickly and accurately produce RNA, overcoming a fundamental limitation of natural enzymes.

The new enzyme, C28, synthesizes RNA with high fidelity, supports long sequences, and enables reverse transcription and DNA-RNA amplification, expanding experimental capabilities.

The National Science Foundation supported the research.

Why the world’s best clean-energy catalysts still fail — and how to fix them? Iridium oxide is one of the best catalysts for making hydrogen fuel, but it’s rare and slowly breaks down inside electrolyzers. In a new study, researchers at Duke University and the University of Pennsylvania captured iridium oxide degrading atom by atom, in real time — revealing that the degradation process is not at all what they expected. Understanding how these materials fail is a critical step toward designing longer-lasting catalysts — and a more sustainable green-energy economy.