Illicit fentanyl use is more than double medical use in US
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Oct-2026 19:16 ET (20-Oct-2026 23:16 GMT/UTC)
The largest study to date that quantifies and compares medical and illegal use of fentanyl in the United States suggests that illicit use is more than twice as common as medically based use. The analysis also shows the risk of a nonfatal overdose is up to three-fold higher in illicit users compared to patients exposed to fentanyl in a medical setting or through a prescription. Overall, the study found that illicit-source fentanyl exposure is linked to a significantly higher risk of opioid-related harmful outcomes than medical-source exposure.
The Land Institute and HudsonAlpha Institute for Biotechnology have assembled the first chromosome-scale, haplotype-phased genomes for Silphium integrifolium (rosinweed, silflower) and Silphium perfoliatum (cup plant, silphie). The findings are published in the journal Nature Communications. This landmark research promises to expand and accelerate the development of more climate-resilient, sustainable perennial crops for food, fiber, forage, and medicines.
Scientists have revealed the DNA identity of the “initiator,” a crucial sequence that kickstarts gene activation. AI analysis of a half million data points deciphered the initiator’s identity. Researchers can use the new information to scan for mutations that may lead to diseases such as cancer.
Traditional field research combined with new technology has revealed a secret to the survival of juvenile salmon as they form in their eggs, especially in low-water years when many do not survive, new research from NOAA Fisheries and the University of California, Davis shows.
Optical fibres carry the global internet because light travels through them with extremely low loss. Researchers at Caltech and the University of Southampton have now adapted flame hydrolysis deposition, a process widely used in optical-fibre manufacturing, to photonic chips. The resulting high-germania-doped microresonators reach ultrahigh Q from telecom to violet wavelengths, opening a scalable route toward fibre-like loss, low-noise lasers, frequency combs and precision photonic systems.