Scientists take aim at a novel target to reduce preterm birth
Peer-Reviewed Publication
Updates every hour. Last Updated: 7-Nov-2025 09:11 ET (7-Nov-2025 14:11 GMT/UTC)
Complement, a component of the innate immune system, has been pinpointed by a research team at the Medical University of South Carolina as playing a key role in inflammatory responses that contribute to fetal neural inflammation and preterm birth, the latter of which represents the primary driver of complications and death in newborns. The team reports its findings in Cells.
Researchers funded by the National Institutes of Health (NIH) have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians in the United States and elsewhere. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit. The results were published today in The New England Journal of Medicine.
Scientists from Auburn University and international collaborators have uncovered the strongest protein-protein bond ever recorded in nature. Their discovery explains why Staphylococcus aureus, a leading cause of skin infections, clings so stubbornly to human skin — and points to new ways of fighting antibiotic-resistant bacteria.