Researchers have developed an ultra-mild bisulfite sequencing method (UMBS-seq) that preserves DNA integrity while delivering highly accurate methylation measurements. The new approach overcomes long-standing limitations of traditional bisulfite and enzymatic methods, enabling more reliable detection of cancer-related epigenetic signals. The technology, published in Nature Communications and licensed to Ellis Bio, could improve liquid biopsy testing and accelerate development of methylation-based diagnostics.

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) survivors encounter rare, life-threatening drug reactions and years of physical, emotional and social consequences long after leaving the hospital, according to a study published today in JAMA Dermatology. 

Young sexual minority men – a term used to describe gay, bisexual, and other men who have sex with men – with attention-deficit/hyperactivity disorder (ADHD) symptoms are more likely to begin using substances such as cigarettes, alcohol, cannabis, stimulants and illicit drugs at an earlier age, according to Rutgers Health researchers.