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Funded Research News

Updates every hour. Last Updated: 10-Sep-2025 01:11 ET (10-Sep-2025 05:11 GMT/UTC)

HPTN 094 study examines a novel way to take addiction care and HIV prevention to people who inject drugs

HIV Prevention Trials Network (HPTN)
Reports and Proceedings

Researchers from the HIV Prevention Trials Network (HPTN) presented results from the HPTN 094 (“INTEGRA”) study at the 2025 Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco. The main findings from this randomized controlled trial that enrolled persons who inject drugs showed that similar numbers of participants were on medication for opioid use disorder (MOUD) and antiretroviral therapy (ART) for HIV care or prevention at 26 weeks post-randomization either to an intervention arm that provided integrated services with peer navigation in a mobile unit or to an active control arm that received navigation to integrated services at available community agencies only. Findings showed about seven percent of participants in both arms were determined as alive and on MOUD, about 35 percent of participants living with HIV were virally suppressed, and between three percent and five percent on HIV pre-exposure prophylaxis (PrEP) at 26 weeks post-randomization.

Funder: NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute on Drug Abuse

Software startup Molecular Intelligence improves structuring molecules from cryo-EM image data

Purdue University
Business Announcement

Purdue University-connected startup Molecular Intelligence supports research scientists in bioengineering, medical science and pharmaceutical companies who use cryo-EM to determine 3D structures of proteins, nucleic acids and other biomolecules. The company's software suite leverages deep learning to enable the identification of atom positions in low-resolution cryo-EM maps. The software then uses those identified atom positions to construct the 3D structures of proteins and DNA/RNA.

Funder: NIH/National Institutes of Health

Socioeconomically disadvantaged people still underusing emergency department services in the wake of the COVID pandemic

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

Socioeconomically disadvantaged groups may still be underusing emergency departments for potentially serious illnesses in the wake of the COVID pandemic, despite an overall rebound in emergency department use by 2022. Most of the rebound had been driven primarily by patients covered by commercial insurance or Medicare fee-for-service. When stratified by insurance type, however, the rebound was found to be significantly lower among patients covered by Medicaid or dual Medicare/Medicaid, who tend to be socioeconomically disadvantaged.

Journal: Health Affairs
Funder: National Heart, Lung, and Blood Institute, NIH/National Institute on Aging

Meningococcal vaccine found to be safe and effective for infants in sub-Saharan Africa

University of Maryland School of Medicine
Peer-Reviewed Publication

University of Maryland School of Medicine (UMSOM) researchers helped conduct an important new global health study that found a vaccine that protects against five strains of meningitis prevalent in sub-Saharan Africa is safe and effective for use in young children beginning at 9 months of age. This study provided evidence that formed the basis for the World Health Organization’s (WHO) decision last year to recommend the pentavalent Men5CV meningitis vaccine for infants ages 9 months and older.

Journal: The Lancet
Funder: NIH/National Institute of Allergy and Infectious Diseases

More hospital rehabilitation may not mean you’re home sooner

University of California - San Francisco
Peer-Reviewed Publication

To help patients recover more quickly, hospitals may provide physical and occupational therapy – especially for older adults to help them preserve or regain function. How much therapy is best, though, isn’t clear.

Journal: Journal of General Internal Medicine
Funder: NIH/National Heart, Lung and Blood Institute, NIH/National Institute on Aging