Every winter, influenza returns with a new variant. People who have previously been infected with or vaccinated against flu may have some protection, but this depends on how well their immune system’s “memory” of the previous virus or vaccine cross-reacts with the new variant. At present, there is no good way to measure this. A new NIH-funded project by researchers at UC Davis and Johns Hopkins Bloomberg School of Public Health aims to solve that problem with a new device to measure this immune system “memory” in the blood. 

The plague is one of the deadliest bacterial infections in human history. An estimated 50 million Europeans died from it in the mid-1300s when it was known as the “Black Death.”

Thanks to improved sanitation, public health measures and antibiotics, the Centers for Disease Control and Prevention now reports an average of only seven human cases of plague in the U.S. each year. While humans are largely safe from it, particularly in the eastern half of the U.S., the disease continues to wipe out prairie dog colonies and infect other rodents in the western half of the U.S.