Investigators at Mass General Brigham have discovered a new pathway that may lead to a treatment for high blood pressure and aortic aneurysms. By creating a new laboratory model for studying these conditions, the team treated hypertension and aortic aneurysms by targeting a protein that they discovered to be involved in the vascular cells’ response to oxidative stress. The findings are published on May 1, 2025 in The Journal of Clinical Investigation.

Acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are the most common pediatric cancers and among the leading causes of death in children.

To improve kids’ chances of survival, early diagnosis and prompt hospital treatment are required. ALL also requires numerous outpatient visits for consistent oral medication. The problem is getting access to such care is much harder for families in some neighborhoods and small towns, according to new research by UC San Francisco.