Researchers found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population. These findings could help clinicians better recognize the disease and develop a standard-of-care, particularly for Amish patients affected by this disease.

Brain tissue studies reveal more beta amyloid and tau accumulation in women with Down syndrome than in men.

Findings emphasize the importance of considering sex in the design of Alzheimer’s research and treatment.

The National Institutes of Health supported the study.

A new study reveals that the legacy of redlining—a discriminatory housing policy from the 1930s—is associated with inequities in rapid access to emergency medical services (EMS) today. These disparities in prehospital care can have serious consequences for patients experiencing life-threatening conditions such as major trauma, stroke, cardiac arrest, or septic shock.

Alcohol has been identified as the third-leading preventable cause of cancer, but little is known about the biological mechanisms behind the association. A new study sheds light on how chronic inflammation related to alcohol consumption accelerates the development of pancreatic cancer.