New research shows that individuals who have recovered from depression are generally less willing to exert effort to pursue potential rewards compared to those who have never experienced depression, unless the rewards are large and highly likely. A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, provides deeper insights into subtle motivational deficits that persist in individuals who have recovered from depression, potentially explaining relapse vulnerability and guiding targeted treatment for sustained recovery and overall patient well-being.