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The Korea Advanced Institute of Science and Technology (KAIST)

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Caption

Figure 1. Schematic diagram of antiviral signal amplification by SLIRP: SLIRP-based mt-dsRNA induction, cytoplasmic accumulation, and strong interferon response induction by positive feedback of immune response activation. Confirmation of the immune regulatory function of SLIRP in defense against autoimmune diseases Sjögren's syndrome, coronavirus, and encephalomyocarditis virus infection.

Credit

Authors: Doyeong Ku, Yewon Yang, Youngran Park, Daesong Jang, Namseok Lee, Yong-ki Lee, Keonyong Lee, Jaeseon Lee, Yeon Bi Han, Soojin Jang, Se Rim Choi, You-Jung Ha, Yong Seok Choi, Woo-Jin Jeong, Yun Jong Lee, Kyung Jin Lee, Seunghee Cha, and Yoosik Kim

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