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16-Nov-2020
X-ray study explores potential of hepatitis C drugs to treat COVID-19
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
Researchers at the Department of Energy's Oak Ridge National Laboratory investigated the binding properties of several hepatitis C drugs to determine how well they inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce. Inhibiting, or blocking, the protease from functioning is vital to stopping the virus from spreading in patients with COVID-19.
- Journal
- Structure
- Funder
- DOE/US Department of Energy, DOE/National Virtual Biotechnology Laboratory, Coronavirus CARES Act
13-Nov-2020
ORNL, partners receive more than $4 million to advance AI control of complex systems
DOE/Oak Ridge National Laboratory
The Department of Energy's Oak Ridge National Laboratory and three partnering institutions have received $4.2 million over three years to apply artificial intelligence to the advancement of complex systems in which human decision making could be enhanced via technology.
5-Nov-2020
Story tips: Ice breaker data, bacterial breakdown, catching heat and finding order
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
ORNL story tips: Ice breaker data, bacterial breakdown, catching heat and finding order
- Funder
- Department of Energy's Office of Science; ORNL Laboratory Directed Research and Development program
29-Oct-2020
ORNL researcher studies individualized isotopes' impact by targeting cancer
DOE/Oak Ridge National Laboratory
A radioisotope researcher in the Radioisotope Science and Technology Division at the Department of Energy's Oak Ridge National Laboratory, Davern is focusing on ways to use nanoparticles -- particles 100 nanometers or smaller that can have special properties -- to contain those radioisotopes and deliver them directly to cancer cells, where they can decay into different isotopes that irradiate those cells.
28-Oct-2020
Oak Ridge National Lab industry collaboration enables job growth, N95 mask production in Florida
DOE/Oak Ridge National Laboratory
A collaboration between the Department of Energy's Oak Ridge National Laboratory and a Florida-based medical device manufacturer has led to the addition of 500 jobs in the Miami area to support the mass production of N95 respirator masks.
27-Oct-2020
Neutrons chart atomic map of COVID-19's viral replication mechanism
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction. Researchers at the Department of Energy's Oak Ridge National Laboratory used neutron scattering to identify key information to improve the effectiveness of drug inhibitors designed to block the virus's replication mechanism.
- Journal
- Journal of Biological Chemistry
- Funder
- DOE/US Department of Energy
26-Oct-2020
On-surface synthesis of graphene nanoribbons could advance quantum devices
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
An international multi-institution team of scientists has synthesized graphene nanoribbons -- ultrathin strips of carbon atoms -- on a titanium dioxide surface using an atomically precise method that removes a barrier for custom-designed carbon nanostructures required for quantum information sciences.
- Journal
- Science
- Funder
- Department of Energy
22-Oct-2020
Colorado School of Mines researchers use neutrons to study weld-induced stress relief
DOE/Oak Ridge National Laboratory
Researchers from the Colorado School of Mines used neutrons at Oak Ridge National Laboratory's High Flux Isotope Reactor to measure residual stress of welds used to make large steel tanks that store molten salts for industrial concentrating solar plants.
19-Oct-2020
Additively manufactured components by ORNL headed for TVA nuclear reactor
DOE/Oak Ridge National Laboratory
ORNL has 3D printed a channel bracket to go into reactors at Browns Ferry Nuclear Plant this spring, to demonstrate the viability of pre-qualified additively manufactured reactor components.