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6-May-2021
ORNL's Sergei Kalinin elected Fellow of the Microscopy Society of America
DOE/Oak Ridge National LaboratoryGrant and Award Announcement
Sergei Kalinin, a scientist and inventor at the Department of Energy's Oak Ridge National Laboratory, has been elected a Fellow of the Microscopy Society of America professional society.
- Funder
- DOE/Energy Office of Science
4-May-2021
ORNL's superb materials expertise, data and AI tools propel progress
DOE/Oak Ridge National Laboratory
At the Department of Energy's Oak Ridge National Laboratory, scientists use artificial intelligence, or AI, to accelerate the discovery and development of materials for energy and information technologies.
3-May-2021
Story tips: Stealthy air leak detection, carbon to chemicals and recycling goes large
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
ORNL story tips: Stealthy air leak detection, carbon to chemicals and recycling goes large.
- Journal
- Nature Communications
- Funder
- Department of Energy Office of Science; DOE Office of Energy Efficiency and Renewable Energy, DOE-EERE Bioenergy Technologies Office
27-Apr-2021
ORNL licenses revolutionary AI system to General Motors for automotive use
DOE/Oak Ridge National LaboratoryBusiness Announcement
The Department of Energy's Oak Ridge National Laboratory has licensed its award-winning artificial intelligence software system, the Multinode Evolutionary Neural Networks for Deep Learning, to General Motors for use in vehicle technology and design.
- Funder
- Department of Energy Office of Science: DOE Office of Energy Efficiency and Renewable Energy's Vehicle Technologies Office
6-Apr-2021
Scientists reveal elusive inner workings of antioxidant enzyme with therapeutic potential
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
The enzyme manganese superoxide dismutase (MnSOD) plays a critical role in maintaining human health by keeping the amount of harmful reactive oxygen molecules in cells under control. By using neutron scattering at Oak Ridge National Laboratory, researchers have now obtained a complete atomic portrait of the enzyme, revealing key information about its catalytic mechanism. The work could help experts develop MnSOD-based treatments and design therapeutics that mimic its antioxidant behavior.
- Journal
- Nature Communications
- Funder
- DOE/US Department of Energy, NASA, Nebraska Research Initiative, Fred & Pamela Buffett NCI Cancer Center
5-Apr-2021
Story tips: Mighty Mo material, fueling retooling, goods on the move, doubling concrete and more
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
ORNL story tips: Mighty Mo material, fueling retooling, goods on the move, doubling concrete and batteries passport.
- Journal
- Construction and Building Materials
- Funder
- Department of Energy's Office of Science; DOE Office of Energy Efficiency and Renewable Energy, Department of Transportation, Building Technologies Office, Vehicle Technologies Office; DOE Office of Fossil Energy; Bureau of Transportation Statistics
31-Mar-2021
Quantum material's subtle spin behavior proves theoretical predictions
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
Using complementary computing calculations and neutron scattering techniques, researchers from the Department of Energy's Oak Ridge and Lawrence Berkeley national laboratories and the University of California, Berkeley, discovered the existence of an elusive type of spin dynamics in a quantum mechanical system.
- Journal
- Nature Physics
- Funder
- DOE/US Department of Energy, Quantum Science Center, Simons Foundation Investigator program
26-Mar-2021
ORNL meets key FDA milestone for cancer-fighting Ac-225 isotope
DOE/Oak Ridge National LaboratoryBusiness Announcement
A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs. The U.S. Food and Drug Administration recently received Oak Ridge National Laboratory's drug master file for actinium-225 nitrate, which lets pharmaceutical companies reference the document to support applications for their own Ac-225-based drugs without disclosing proprietary information.
- Funder
- U.S. Department of Energy Isotope Program
23-Mar-2021
Neutrons reveal unpredicted binding between SARS-CoV-2, hepatitis C antiviral drug
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
Researchers at the Oak Ridge National Laboratory used neutron scattering to investigate the interactions between telaprevir, a drug used to treat hepatitis C viral infection, and the SARS-CoV-2 main protease, the enzyme responsible for enabling the virus to reproduce. Unforeseen changes in the electric charges were discovered in the drug binding site of the protease enzyme that were not predicted by prevailing computer simulations. The research provides key insights for advancing drug design and drug repurposing efforts to treat COVID-19.
- Journal
- Journal of Medicinal Chemistry
- Funder
- DOE/US Department of Energy, DOE/National Virtual Biotechnology Laboratory, Coronavirus CARES Act