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18-Jun-2001
Obesity-related gene in mouse discovered at ORNL
DOE/Oak Ridge National Laboratory
Some mice born at ORNL have grown dangerously fat, even though they have been on
a low-fat diet since birth. Although they do not appear overweight, these mice have a
mutated gene that plays a strong role in causing obesity in the form of internal fat
deposits that are hazardous to their health.
18-Jun-2001
Curing cancer in mice
DOE/Oak Ridge National Laboratory
ORNL researchers have shown that a radioisotope-bearing antibody can target the blood
vessels of lung tumors in mice, destroying the tumors.
18-Jun-2001
Complex biological systems in mice
DOE/Oak Ridge National Laboratory
Using genetic engineering, gene microarrays, and computational technologies, ORNL
researchers are deciphering genetic variations in the skin that lead to increased risk of
disease from environmental factors.
18-Jun-2001
Search for signs of inflammatory disease
DOE/Oak Ridge National Laboratory
You fall on your shoulder and tear some cartilage, causing bone to rub against bone.
Your shoulder becomes inflamed and begins to hurt because cytokine, a small signal
protein secreted by your immune system, has recruited white blood cells to clean up the
damage.
18-Jun-2001
Mouse models for the human disease of chronic hereditary tyrosinemia
DOE/Oak Ridge National Laboratory
When a section of mouse chromosome 7 containing the coat color c gene is deleted by
exposing mice to radiation, "albino" mice are born with a white, hairless coat.
23-Jan-2001
Story tips from the Department of Energy's Oak Ridge National Laboratory, January 2001
DOE/Oak Ridge National LaboratoryPeer-Reviewed Publication
HEALTH-Better CPR a heartbeat away? TRANSPORTATION-Safer
Skies. ENVIRONMENT-Ocean's biology under spotlight. VEHICLE
SAFETY-Driving dangerously.
1-Jan-2001
Systems biology
DOE/Oak Ridge National Laboratory
ORNL scientists are conducting research in functional genomics—the study of genomes to
determine the biological function of all the genes and their products—and proteomics—the
study of the full set of proteins encoded by a genome.
19-Dec-2000
The crystal robot
DOE/Oak Ridge National Laboratory
Innovative robotics designed and built by Lab
researchers will grow protein crystals for
experimentation at a rate once only dreamed of.
19-Dec-2000
Picturing proteins
DOE/Oak Ridge National Laboratory
Electron microscopy and spectroscopy techniques are
making it possible for scientists to create 3-D images of
protein complexes that are unsuitable for x-ray
crystallography.